/*
 * 肺がん薬一覧
 * 基本レイアウト・部品は Bootstrap 5、色・文字・影は Kadahutu Theme の変数を継承。
 */

.kadakusu-cancer-drug-page {
	background-color: var(--bg-cream);
}

.kadakusu-drug-index {
	color: var(--text-dark);
}

.kadakusu-drug-directory {
	color: var(--text-dark);
}

.kadakusu-directory-intro {
	margin-bottom: 2.5rem;
	padding: 1rem 1.25rem;
	border-left: 4px solid var(--kada-orange);
	border-radius: 0 .5rem .5rem 0;
	background: #fff;
	box-shadow: var(--shadow-sm);
}

.kadakusu-directory-intro p {
	margin: 0;
	color: var(--text-gray);
	font-size: .9rem;
}

.kadakusu-directory-intro i {
	color: var(--kada-orange);
}

.kadakusu-directory-jump {
	margin-bottom: 3.5rem;
	padding: 1.25rem;
	border: 1px solid #e8e4da;
	border-radius: .9rem;
	background: #fff;
	box-shadow: var(--shadow-sm);
}

.kadakusu-directory-jump__heading {
	display: flex;
	gap: .85rem;
	align-items: center;
	margin-bottom: 1rem;
}

.kadakusu-directory-jump__heading > span {
	display: inline-flex;
	width: 2.5rem;
	height: 2.5rem;
	flex: 0 0 auto;
	align-items: center;
	justify-content: center;
	border-radius: 50%;
	background: rgba(var(--kada-orange-rgb), .14);
	color: var(--kada-orange);
}

.kadakusu-directory-jump__heading h2 {
	margin: 0;
	color: var(--kada-brown);
	font-size: 1.15rem;
}

.kadakusu-directory-jump__heading p {
	margin: .15rem 0 0;
	color: var(--text-gray);
	font-size: .75rem;
}

.kadakusu-directory-jump__list {
	display: grid;
	grid-template-columns: repeat(3, minmax(0, 1fr));
	gap: .65rem;
	margin: 0;
	padding: 0;
	list-style: none;
}

.kadakusu-directory-jump__list a {
	display: grid;
	grid-template-columns: 1.25rem minmax(0, 1fr) auto;
	gap: .6rem;
	align-items: center;
	min-height: 2.9rem;
	padding: .7rem .8rem;
	border: 1px solid #e8e4da;
	border-radius: .6rem;
	background: #fffaf3;
	color: var(--kada-brown);
	font-size: .84rem;
	font-weight: 700;
	line-height: 1.35;
	text-decoration: none;
	transition: border-color .2s ease, background-color .2s ease, color .2s ease, transform .2s ease;
}

.kadakusu-directory-jump__list a > i:first-child {
	color: var(--kada-orange);
	text-align: center;
}

.kadakusu-directory-jump__arrow {
	color: #c7b9a7;
	font-size: .7rem;
}

.kadakusu-directory-jump__list a:hover,
.kadakusu-directory-jump__list a:focus-visible {
	border-color: var(--kada-orange);
	background: #fff3df;
	color: var(--kada-brown);
	text-decoration: none;
	transform: translateY(-1px);
}

.kadakusu-cancer-directory {
	margin-bottom: 4rem;
}
.kadakusu-cancer-directory__title {
	scroll-margin-top: 5rem;
	margin: 0 0 2rem;
	color: var(--kada-brown);
	font-size: clamp(1.65rem, 4vw, 2.25rem);
}

.kadakusu-cancer-directory__title:target {
	border-radius: .4rem;
	outline: 3px solid rgba(var(--kada-orange-rgb), .22);
	outline-offset: .35rem;
}

.kadakusu-disease-group + .kadakusu-disease-group {
	margin-top: 3.5rem;
}

.kadakusu-disease-group__heading {
	display: flex;
	gap: .85rem;
	align-items: center;
	margin-bottom: 1.25rem;
	padding-bottom: .85rem;
	border-bottom: 1px solid #e8e4da;
}

.kadakusu-disease-group__heading > span {
	display: inline-flex;
	width: 2.5rem;
	height: 2.5rem;
	align-items: center;
	justify-content: center;
	border-radius: .5rem;
	background: linear-gradient(90deg, var(--kada-orange) 0%, #f7931e 100%);
	color: #fff;
	box-shadow: var(--shadow-sm);
}

.kadakusu-disease-group__heading h3 {
	margin: 0;
	color: var(--kada-brown);
	font-size: 1.4rem;
}

.kadakusu-disease-card.card {
	border: 1px solid #e8e4da;
	border-radius: .75rem;
	background: #fff;
	box-shadow: var(--shadow-sm);
	color: inherit;
	text-decoration: none;
	transition: border-color .2s ease, box-shadow .2s ease, transform .2s ease;
}

.kadakusu-disease-card.card:hover {
	border-color: var(--kada-orange);
	box-shadow: var(--shadow-md);
	color: inherit;
	text-decoration: none;
	background-color: #efefef;
	transform: translateY(-3px);
}

.kadakusu-disease-card .card-body {
	display: grid;
	grid-template-columns: auto minmax(0, 1fr) auto;
	gap: 1rem;
	align-items: center;
	padding: 1.25rem;
}

.kadakusu-disease-card__icon {
	display: inline-flex;
	width: 2.75rem;
	height: 2.75rem;
	align-items: center;
	justify-content: center;
	border-radius: 50%;
	background: rgba(var(--kada-orange-rgb), .14);
	color: var(--kada-orange);
	font-size: 1.1rem;
}

.kadakusu-disease-card h4 {
	margin: 0 0 .25rem;
	color: var(--kada-brown);
	font-size: 1rem;
}

.kadakusu-disease-card p {
	margin: 0;
	color: var(--text-gray);
	font-size: .75rem;
}

.kadakusu-disease-card p strong {
	color: var(--kada-orange);
	font-size: .95rem;
}

.kadakusu-disease-card__arrow {
	color: #c7b9a7;
	font-size: .8rem;
	transition: color .2s ease, transform .2s ease;
}

.kadakusu-disease-card:hover .kadakusu-disease-card__arrow {
	color: var(--kada-orange);
	transform: translateX(3px);
}

.kadakusu-drug-hero {
	padding: 0 0 3rem;
}

.kadakusu-drug-hero .kadakusu-breadcrumb__list {
	flex-wrap: wrap;
	margin-bottom: 0;
}

.kadakusu-hero-panel {
	overflow: hidden;
	border-radius: 1rem;
	background:
		radial-gradient(circle at 90% 15%, rgba(var(--kada-orange-rgb), .16) 0 9%, transparent 9.5%),
		linear-gradient(135deg, #fff 0%, #fff8ee 100%);
	box-shadow: var(--shadow-md);
}

.kadakusu-eyebrow,
.kadakusu-results-kicker {
	margin: 0 0 .5rem;
	color: var(--kada-orange);
	font-size: .8rem;
	font-weight: 700;
	letter-spacing: .08em;
}

.kadakusu-drug-hero h1 {
	margin-bottom: 1rem;
	color: var(--kada-brown);
	font-size: clamp(2.25rem, 5vw, 3.75rem);
	line-height: 1.2;
}

.kadakusu-hero-copy {
	max-width: 45rem;
	color: var(--text-gray);
	font-size: 1rem;
}

.kadakusu-hero-count {
	display: grid;
	grid-template-columns: auto auto;
	gap: 0 .75rem;
	min-width: 13rem;
	align-items: center;
	padding: 1.5rem;
	border: 2px solid rgba(var(--kada-orange-rgb), .18);
	border-radius: .75rem;
	background: rgba(255, 255, 255, .9);
	color: var(--kada-brown);
	text-align: left;
}

.kadakusu-hero-count > i {
	grid-row: 1 / 4;
	color: var(--kada-orange);
	font-size: 2.4rem;
}

.kadakusu-hero-count strong {
	font-size: 2rem;
	line-height: 1;
}

.kadakusu-hero-count span {
	font-size: .9rem;
	font-weight: 700;
}

.kadakusu-hero-count small {
	color: var(--text-gray);
	font-size: .7rem;
}

.kadakusu-filter-panel {
	position: sticky;
	border: 1px solid #e8e4da;
	border-radius: .75rem;
	background: #fff;
	box-shadow: var(--shadow-sm);
}
.kadakusu-filter-panel.card {
	background: #fff;
	border: 0;
}

.kadakusu-filter-title {
	display: flex;
	justify-content: space-between;
	gap: .75rem;
	align-items: center;
	margin-bottom: 1.25rem;
	padding-bottom: .9rem;
	border-bottom: 2px solid rgba(var(--kada-orange-rgb), .2);
}

.kadakusu-filter-title h2 {
	margin: 0;
	color: var(--kada-brown);
	font-size: 1.05rem;
}

.kadakusu-filter-title .btn {
	padding: .2rem;
	color: var(--text-gray);
	font-size: .72rem;
	text-decoration: none;
}

.kadakusu-filter-title .btn:hover {
	color: var(--kada-orange);
}

.kadakusu-search-label,
.kadakusu-filter-group legend {
	margin-bottom: .5rem;
	color: var(--kada-brown);
	font-size: .9rem;
	font-weight: 700;
}

.kadakusu-filter-panel .input-group-text {
	color: var(--kada-orange);
}

.kadakusu-filter-group {
	display: grid;
	gap: .25rem;
	margin: 1.25rem 0 0;
	padding: 1.25rem 0 0;
	border: 0;
	border-top: 1px solid #e8e4da;
}

.kadakusu-filter-group label {
	display: grid;
	grid-template-columns: minmax(0, 1fr) auto;
	gap: .5rem;
	align-items: center;
	margin: 0;
	padding: .7rem .75rem;
	border: 0;
	border-radius: .5rem;
	color: var(--text-gray);
	cursor: pointer;
	font-size: .82rem;
	line-height: 1.35;
}
.kadakusu-filter-group label:last-child {
	border-radius: .5rem;
}

.kadakusu-filter-group label i {
	width: 1rem;
	color: var(--kada-orange);
	text-align: center;
}

.kadakusu-filter-group label:hover,
.kadakusu-filter-group label:hover {
	background-color: rgba(var(--kada-orange-rgb), .12);
	color: var(--kada-brown);
}

.kadakusu-filter-group label.is-active {
	border-color: var(--kada-orange);
	background: linear-gradient(90deg, var(--kada-orange) 0%, #f7931e 100%);
	box-shadow: 0 3px 9px rgba(var(--kada-orange-rgb), .25);
	color: #fff;
	font-weight: 700;
}
.kadakusu-filter-group label.is-active:hover {
	color: var(--bs-list-group-action-hover-color);
}

.kadakusu-filter-group label > span {
	display: flex;
	min-width: 0;
	align-items: center;
}

.kadakusu-filter-group label.is-active > span::after {
	margin-left: auto;
	padding-left: .5rem;
	content: "\f00c";
	font-family: "Font Awesome 7 Free";
	font-weight: 900;
}

.kadakusu-filter-group label.is-active i {
	color: #fff;
}

.kadakusu-filter-group label.is-active .badge {
	background: #fff;
	color: var(--kada-orange);
}

.kadakusu-filter-group input {
	position: absolute;
	width: 1px;
	height: 1px;
	overflow: hidden;
	clip: rect(0, 0, 0, 0);
	white-space: nowrap;
	clip-path: inset(50%);
}

.kadakusu-filter-group label:focus-within {
	outline: 2px solid var(--bs-link-color);
	outline-offset: 2px;
}

.kadakusu-filter-group .badge {
	background: #fff;
	color: var(--text-gray);
	font-weight: 500;
}

.kadakusu-filter-group .kadakusu-scope-help {
	padding: .55rem .65rem;
	color: var(--text-gray);
	font-size: .68rem;
	line-height: 1.55;
}

.kadakusu-filter-group .kadakusu-scope-help i {
	color: var(--kada-orange);
}

.kadakusu-active-filter-wrap {
	margin-top: 1.25rem;
	padding-top: 1.1rem;
	border-top: 1px solid #e8e4da;
}

.kadakusu-active-filter-title {
	margin-bottom: .55rem;
	color: var(--kada-brown);
	font-size: .75rem;
	font-weight: 700;
}

.kadakusu-active-filter-title i {
	color: var(--kada-orange);
}

.kadakusu-active-filters {
	display: flex;
	flex-wrap: wrap;
	gap: .35rem;
}

.kadakusu-filter-chip {
	display: inline-flex;
	align-items: center;
	padding: .3rem .6rem;
	border-radius: 999px;
	background: var(--kada-brown);
	color: #fff;
	font-size: .7rem;
	font-weight: 700;
	line-height: 1.35;
}

.kadakusu-filter-chip::before {
	margin-right: .35rem;
	content: "\f00c";
	font-family: "Font Awesome 7 Free";
	font-weight: 900;
}

.kadakusu-filter-chip.is-default {
	background: #eee9df;
	color: var(--text-gray);
	font-weight: 500;
}

.kadakusu-filter-summary {
	margin-top: 1.25rem;
	padding: .75rem;
	border-radius: .5rem;
	background: rgba(var(--kada-orange-rgb), .12);
	color: var(--kada-brown);
	font-size: .82rem;
	text-align: center;
}

.kadakusu-filter-summary strong {
	color: var(--kada-orange);
	font-size: 1.1rem;
}

.kadakusu-results-heading {
	display: flex;
	justify-content: space-between;
	gap: 1.5rem;
	align-items: end;
	margin-bottom: 2rem;
	padding-bottom: 1.25rem;
	border-bottom: 1px solid #e8e4da;
}

.kadakusu-results-heading h2 {
	margin: 0;
	color: var(--kada-brown);
	font-size: clamp(1.65rem, 4vw, 2.25rem);
}

.kadakusu-results-heading > p {
	margin: 0;
	color: var(--text-gray);
	font-size: .8rem;
	white-space: nowrap;
	display: flex;
	align-items: end;
}

.kadakusu-results-heading > p strong {
	color: var(--kada-orange);
	font-size: 2.4rem;
	line-height: 1;
}

.kadakusu-category-section + .kadakusu-category-section {
	margin-top: 3.5rem;
}

.kadakusu-category-heading {
	display: grid;
	grid-template-columns: auto minmax(0, 1fr) auto;
	gap: 1rem;
	align-items: center;
	margin-bottom: 1rem;
}

.kadakusu-category-mark {
	display: inline-flex;
	width: 3rem;
	height: 3rem;
	align-items: center;
	justify-content: center;
	border-radius: .5rem;
	background: linear-gradient(90deg, var(--kada-orange) 0%, #f7931e 100%);
	color: #fff;
	font-size: 1.25rem;
	box-shadow: var(--shadow-sm);
}

.kadakusu-category-heading h3 {
	margin: 0 0 .15rem;
	color: var(--kada-brown);
	font-size: 1.25rem;
}

.kadakusu-category-heading p {
	margin: 0;
	color: var(--text-gray);
	font-size: .8rem;
}

.kadakusu-category-count {
	background-color: var(--kada-orange);
	color: var(--kada-brown);
	font-weight: 500;
}

.kadakusu-drug-card {
	overflow: hidden;
	border: 1px solid #e8e4da;
	border-radius: .75rem;
	background: #fff;
	box-shadow: var(--shadow-sm);
	transition: border-color .25s ease, box-shadow .25s ease, transform .25s ease;
}

.kadakusu-drug-card:hover {
	border-color: var(--kada-orange);
	box-shadow: var(--shadow-md);
	transform: translateY(-3px);
}

.kadakusu-drug-card .card-body {
	padding: 1.35rem;
}

.kadakusu-card-topline {
	display: flex;
	flex-wrap: wrap;
	gap: .4rem;
	align-items: center;
	margin-bottom: .8rem;
}

.kadakusu-card-topline > span {
	background: rgba(var(--kada-orange-rgb), .14);
	color: #b64d18;
	min-height: 22px;
	border-radius: 4px;
}

.kadakusu-card-topline small {
	color: var(--text-gray);
	font-size: .7rem;
}

.kadakusu-drug-card h4 {
	margin: 0;
	font-size: 1.15rem;
	line-height: 1.45;
	overflow-wrap: anywhere;
}

.kadakusu-drug-card h4 a {
	color: var(--kada-brown);
}

.kadakusu-drug-card h4 a:hover {
	color: var(--bs-link-color);
	text-decoration: none;
}

.kadakusu-generic-name {
	margin: .4rem 0 0;
	color: var(--text-gray);
	font-size: .75rem;
	line-height: 1.5;
	overflow-wrap: anywhere;
}

.kadakusu-indication {
	display: -webkit-box;
	margin: .9rem 0 1.25rem;
	overflow: hidden;
	color: var(--text-gray);
	font-size: .82rem;
	line-height: 1.7;
	-webkit-box-orient: vertical;
	-webkit-line-clamp: 3;
}

.kadakusu-card-link {
	font-size: .82rem;
	font-weight: 700;
}

.kadakusu-card-link:hover {
	text-decoration: none;
}

.kadakusu-medical-note {
	display: grid;
	grid-template-columns: auto minmax(0, 1fr);
	gap: 1rem;
	margin-top: 4rem;
	padding: 1.5rem;
}

.kadakusu-note-mark {
	color: var(--primary-orange);
	font-size: 1.5rem;
}

.kadakusu-medical-note h2 {
	margin: 0 0 .5rem;
	font-size: 1rem;
}

.kadakusu-medical-note p {
	margin: 0;
	color: var(--text-gray);
	font-size: .78rem;
	line-height: 1.8;
}

.kadakusu-medical-note .kadakusu-note-links {
	margin-top: .5rem;
}

.kadakusu-no-data {
	padding: 3rem 1.5rem;
	border: 1px dashed #d6cbbb;
	border-radius: .75rem;
	background: #fff;
	text-align: center;
}

.kadakusu-no-data h3 {
	margin: 0 0 .5rem;
	color: var(--kada-brown);
	font-size: 1.2rem;
}

.kadakusu-no-data p {
	margin: 0;
	color: var(--text-gray);
	font-size: .85rem;
}

.kadakusu-drug-card[hidden],
.kadakusu-category-section[hidden],
.kadakusu-drug-col[hidden] {
	display: none !important;
}

@media (max-width: 991.98px) {
	.kadakusu-directory-jump__list {
		grid-template-columns: repeat(2, minmax(0, 1fr));
	}

	.kadakusu-filter-panel {
		position: static;
	}

	.kadakusu-filter-group {
		grid-template-columns: repeat(3, minmax(0, 1fr));
	}

	.kadakusu-filter-group legend {
		grid-column: 1 / -1;
	}
}

@media (max-width: 575.98px) {
	.kadakusu-directory-jump {
		margin-bottom: 2.5rem;
		padding: 1rem;
	}

	.kadakusu-directory-jump__list {
		gap: .5rem;
	}

	.kadakusu-directory-jump__list a {
		grid-template-columns: 1rem minmax(0, 1fr);
		gap: .45rem;
		min-height: 3rem;
		padding: .65rem;
		font-size: .76rem;
	}

	.kadakusu-directory-jump__arrow {
		display: none;
	}

	.kadakusu-drug-hero {
		padding-bottom: 2rem;
	}

	.kadakusu-hero-count {
		min-width: 0;
	}

	.kadakusu-filter-group {
		grid-template-columns: repeat(2, minmax(0, 1fr));
	}

	.kadakusu-results-heading {
		align-items: start;
	}

	.kadakusu-category-heading {
		grid-template-columns: auto minmax(0, 1fr);
	}

	.kadakusu-category-count {
		display: none;
	}

	.kadakusu-medical-note {
		grid-template-columns: 1fr;
	}
}

@media (prefers-reduced-motion: reduce) {
	.kadakusu-drug-card,
	.kadakusu-disease-card,
	.kadakusu-disease-card__arrow,
	.kadakusu-directory-jump__list a {
		transition: none;
	}
}